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Our 6 Best Weed Killer Picks (2025)

Written by
Stephanie Minasian-Koncewicz
Written by
Stephanie Minasian-Koncewicz
Updated 04/28/2025

Weeds in your lawn and garden can steal nutrients and water away from your plants, and can even steal sunshine. Choosing the right weed killer is key to dealing with this problem while leaving your lawn intact.

After evaluating dozens of the top weed killers on the market, I recommend Green Gobbler Vinegar Weed & Grass Killer as my top choice. Below, I review all of my top picks, along with their key features, benefits, and limitations to provide you with all you need to make an informed decision.

Top 6 Weed Killers


Compare Top Weed Killers

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Product Targets OMRI Listed Quantity
Green Gobbler Vinegar Weed & Grass KillerCheck Price
Crabgrass, dandelions, clovers, and moreYes32 ounces
RM43 43% Glyphosate Plus Weed PreventerCheck Price
Brush, grasses, trees, vines, weedsNo128 ounces(1gal)
Spectracide Weed & Grass KillerCheck Price
All vegetationNo64 ounces
Roundup All-in-One Lawn Weed KillerCheck Price
Crabgrass, dandelions, nutsedge, and moreNo170 ounces (1.33 gal)
Ortho GroundClear Weed & Grass KillerCheck Price
All weeds and grassesYes128 ounces (1 gal)

Weed Killer Terms To Know

  • OMRI: OMRI stands for the Organic Materials Review Institute. Weed killers that are OMRI-listed are certified for use in organic production.

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Best Overall

Green Gobbler Vinegar Weed & Grass Killer

Courtesy Amazon

Good for: Homeowners with pets who are looking to kill weeds in their driveway or walkway.

This natural weed killer from Green Gobbler is effective on surfaces ranging from sidewalks to flower beds without using harsh chemicals. It provides fast-acting, visible results within 24 hours of application. What I like best of all is that this vinegar-based weed-killing formula is pet-friendly and non-toxic.

Courtesy Amazon
$34.98 At Amazon
Prices taken at time of publishing.

Pros and Cons of Green Gobbler Vinegar Weed & Grass Killer

Pros
  • Safe for use around pets
  • Glyphosate-free vinegar formula is 4x stronger than table vinegar
  • Doesn’t require dilution
Cons
  • Not grass-safe
  • Gives off a strong odor

What People Are Saying About The Green Gobbler Vinegar Weed & Grass Killer

According to my verified buyer research, customers who left positive reviews liked that this product was inexpensive and safe for families with children and pets. However, I also found reviews from a minority of dissatisfied customers that said it left an unpleasant smell and caused damage to wood surfaces.

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Best Weed Killer for Large Areas

RM43 43% Glyphosate Plus Weed Preventer

Courtesy Amazon

Good for: Customers looking for a combination weed killer and preventive for hard surfaces such as driveways or pavement.

This formula contains 43% glyphosate, an ingredient that kills existing weeds and sprouts and prevents the germination of new weeds. RM43’s pre-emergent weed preventer is especially useful for driveways, manicured walkways, gravel, and pavement. One gallon of concentrated liquid covers over 17,000 square feet.

Courtesy Amazon
$85.59 – At Amazon
Prices taken at time of publishing.

Pros and Cons of RM43 43% Glyphosate Plus Weed Preventer

Pros
  • High concentration works as an effective pre-emergent herbicide
  • Works well for targeted or generalized applications
  • Single application stays effective for up to 1 year
Cons
  • Application requires users to wear personal safety gear
  • Eliminates desirable vegetation if not used precisely

What People Are Saying About The RM43 43% Glyphosate Plus Weed Preventer

My verified-buyer evaluations showed a majority of highly positive reviews, and many customers stated this weed killer worked well on large areas and was simple to use. However, I found that a handful of dissatisfied customers said it took too long to kick in or was as effective as cheaper, generic brands.

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Best Weed and Grass Killer

Spectracide Weed & Grass Killer

Courtesy Amazon

Good for: Homeowners looking to kill weeds and grass in flower beds or near fences.

This weed killer concentrate produces visible results within 3 hours of application. Spectracide controls weeds and all species of grass, so avoid using it on turfgrass. Instead, apply it precisely to areas like driveways, fences, flower beds, shrubs, and other non-grassy terrain. With multiple size and quantity options, you can choose the option that meets your yard’s specific needs best.

Courtesy Amazon
$28.28 – At Amazon
Prices taken at time of publishing.

Pros and Cons of Spectracide Weed & Grass Killer

Pros
  • Yields visible results within 3 hours of application
  • Becomes rainproof within 15 minutes of application
  • Effective on driveways, fencing, flower beds, around shrubbery, and on sidewalks
Cons
  • Requires manual dilution
  • Herbicidal compounds can damage lawns

What People Are Saying About The Spectracide Weed & Grass Killer

My customer research revealed many happy customers who said this product was long-lasting, fast-working, and persistent with tough weeds. However, I encountered some critical other reviews in which customers claimed that it caused damage to lawns and that it didn’t work as advertised.

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Best Weed Killer for Lawns

Roundup All-in-One Lawn Weed Killer

Courtesy Amazon

Good for: Customers looking to tread weed growth in their lawns.

With the ability to kill over 250 types of weeds, including crabgrass, dandelions, and clovers, this herbicide eliminates almost every type of pesky weed it encounters. Roundup’s All-in-One formula won’t damage lawn grass, making it an ideal (albeit extremely chemically potent) lawn care formula.

Courtesy Amazon
$41.97 – At Amazon
Prices taken at time of publishing.

Pros and Cons of Roundup All-in-One Lawn Weed Killer

Pros
  • Sold in concentrated and ready-to-spray formulas
  • Becomes rainproof within 3 hours of application
  • Targets weeds at the root
Cons
  • Not safe for use around pets
  • May require multiple applications in some cases

What People Are Saying About The Roundup All-in-One Lawn Weed Killer

I discovered that buyers who liked this weed killer said that it was easy to spread and killed multiple types of plants with a minimal amount of spray. On the other hand, my research also revealed some negative reviews due to Roundup’s toxic ingredients, while others were let down that it did not have a large coverage area.

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Best Weed Killer for Flower Beds

Ortho GroundClear Weed & Grass Killer

Courtesy Amazon

Good for: Customers looking to treat a variety of weeds in their flower beds.

With visible results in just 15 minutes, GroundClear’s weed and grass killer can eliminate unwanted vegetation from your flower bed or garden quickly. The ready-to-spray formula becomes rainproof in 2 hours and is particularly effective on densely packed terrain as well as fruit and vegetable garden beds.

Courtesy Amazon
$21.17 – At Amazon
Prices taken at time of publishing.

Pros and Cons of Ortho GroundClear Weed & Grass Killer

Pros
  • Becomes rainproof within 2 hours of application
  • OMRI-listed as safe for organic gardens
  • Works on hardscapes, landscape beds, and troubled vegetable gardens
Cons
  • Eliminates all forms of vegetation exposed to it
  • Significantly less effective when applied to wet vegetation

What People Are Saying About The Ortho GroundClear Weed & Grass Killer

According to my research, satisfied customers said this weed killer worked quickly, didn’t kill wanted plants, and featured a simple-to-operate nozzle and wand. However, my research also revealed that a few buyers found heavy applications ineffective at eliminating weeds entirely.

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Best Weed Preventer

Preen Garden Weed Preventer

Courtesy Amazon

Good for: Homeowners who want to get out ahead of weeds growing in their lawns or gardens.

Killing weeds that already exist is one thing, but preventing them in the first place is even better. This pre-emergent killer can block weeds around trees and shrubs, keeping your landscaping pristine. Application of this preventer can stop weeds for up to six months.

Courtesy Amazon
$21.87 – At Amazon
Prices taken at time of publishing.

Pros and Cons of Preen Garden Weed Preventer

Pros
  • Can be used on over 600 types of perennials, groundcovers, shrubs, and trees
  • Has a flip-top applicator that makes it easy to apply and ensures you don’t overuse
  • Can cover over 800 square feet in one bottle
Cons
  • Not intended for use on lawns or vegetable gardens
  • Cannot be purchased in the state of New York

What People Are Saying About The Preen Garden Weed Preventer

We found that customers who gave this weed preventer a positive review liked that it was easy to apply and was long-lasting. Others noted how effective it was when used in flower beds. However, there were some reviews that felt this weed preventer was ineffective against uprooted weeds, and others said the directions were difficult to follow.


Weed Killer Buying Guide

Not all weed killers work well for every surface or weed. When deciding on a weed killer, it’s important to consider the type of weed you’re looking to combat, as well as the growth stage of the weed. Read the guide below for more information about choosing the best weed killer.

What are the various types of weed control?

Different types of weed killers are recommended for different types of plants and areas of application. Here are some common types of weed killers to look out for.

Contact Herbicides

This type of weed killer kills plants as soon as it makes contact with them. Contact weed killers don’t attack the root system. Instead, they weaken the plant after two or more applications. This type of weed killer is effective for annual weeds that consistently reappear.

Residual Herbicides

These weed killers poison the soil, killing all plants within the treated area. They can be long-lasting, so avoid using this type of weed killer in areas frequented by pets or containing edible plants.

Systemic Herbicides

Systemic weed killers are applied directly to the foliage of a plant. They take several weeks to start working, but they fight the plant’s internal root system. This type of weed killer addresses dandelions, poison ivy, and other hard-to-kill plants.

What is weed emergence?

Emergence refers to how far along the weed’s growth cycle that weed killer must be applied. Some weed killers are pre-emergent, meaning they should be applied to prevent weeds from growing.

Post-emergent weed killers are used for weeds that have already sprouted. They kill the plant while also ensuring it doesn’t grow back.

What’s the difference between selective and non-selective weed killers?

If you’re using a weed killer on flower beds or gardens, using selective weed killers is critical, as they avoid beneficial plants and solely target weeds. Meanwhile, non-selective weed killers destroy all plants in the vicinity.


Common Weed Types

When it comes to weeds that can damage your lawn, some are particularly invasive and detrimental. Here are some of the most common weeds to look out for in your lawn: 

Crabgrass

Crabgrass is an annual grass weed that spreads rapidly, forming dense patches that can choke out desirable grass species. It thrives in bare or thin areas of the lawn and can quickly take over your lawn if you don’t actively control it.

Dandelion

Dandelions are perennial broadleaf weeds with a deep taproot that allows them to survive and reproduce in various conditions. Their bright yellow flowers give way to fluffy seed heads that can disperse seeds over large areas, making them difficult to eradicate.

Broadleaf Plantain

Broadleaf plantain is a perennial weed with large, oval-shaped leaves that form a rosette pattern close to the ground. These weeds can tolerate compacted soil and spread rapidly. Plantain weeds are highly adaptable and can be challenging to eliminate once they begin to spread.

Common Purslane

Purslane is an annual succulent weed that forms low-lying mats. It has thick, fleshy leaves and can produce an abundance of seeds. Purslane is known for its ability to tolerate dry conditions and can quickly invade garden beds.

Creeping Charlie

Also known as ground ivy, creeping Charlie is a perennial weed that spreads by creeping stems. It forms dense mats and can smother grass and other plants. Creeping Charlie has vigorous growth and resilience, making it particularly difficult to control. 

Canada Thistle

Canada thistle is a perennial weed with prickly leaves and pink or purple flowers. It spreads through an extensive root system and can quickly colonize large areas. 

Japanese Knotweed

Japanese knotweed is an extremely invasive perennial plant that can grow rapidly, reaching heights of several feet at full growth. Its extensive root system can damage structures and disrupt native plant communities. Eradicating Japanese knotweed typically requires professional assistance.


Weed Killer FAQs

How do weed killers work?

Generally, weed killers are herbicides that interfere with weed growth by either destroying their root formation or restricting the growth and development of their cells, causing them to eventually die.

Are weed killers dangerous around pets?

It depends on the weed killer. Some aren’t safe for households with pets, while others are safe once dry. The safest option is a weed killer with an organic formula.

For specific guidance on herbicides and active ingredients to look out for, visit the Environmental Protection Agency (EPA) website.

What does OMRI mean?

OMRI stands for the Organic Materials Review Institute, a non-profit organization that provides independent reviews of products for organic farming and processing. OMRI reviews the ingredients and manufacturing processes to ensure they meet organic standards, and organic certifiers use their evaluations to determine if products are allowed for use in organic production.

What are the best weed killers for organic gardens?

Organic gardeners may prefer natural weed killers that vinegar, citric acid, clove oil, and other organic garden-friendly ingredients instead of harsh, noxious chemicals.

However, it’s important to note that even natural weed killers can harm desirable plants if not used correctly and can be toxic if consumed, so always read and follow the instructions carefully.

What is Glyphosate?

According to the EPA, “glyphosate is a widely used herbicide that controls broadleaf weeds and grasses.” It was approved for use in the United States in 1974 and continues to undergo re-evaluation and review by the EPA every 15 years.

How long does it take for weed killers to work?

Typical weed killers will take anywhere from two to six days to kill the root of a plant. Certain herbicides will produce faster results, but these herbicides kill the flowering part of the plant and not its root system.


Our Methodology

To provide our readers with the best weed killer recommendations possible, we rely on several key sources of information to help guide our selection process.

Initial Research: Our research process began by generating a list of weed killers with a significant number of verified buyer reviews and an average customer review rating of 4–5 stars. We looked at positive and negative reviews alike, focusing on information from both satisfied and critical buyers. 

Expert Insights: Through our years of experience, we’ve learned that listening to what others have to say is critical to building accurate, well-rounded articles. To complement our in-house expertise, our team looked for information from trusted publications and subject matter experts. We also drew insights from reader contributions.

Final Product Selection: We then pared the list down further by comparing each weed killer’s pros, cons, and means of application, then eliminating formulas that posed major health and safety concerns. We did all of this to find the best-in-class options for various vegetation types and scenarios.


Why You Can Trust Us

This Old House has empowered homeowners and DIYers for more than four decades with top-notch home improvement advice in the form of television programs, print media, and digital content. 

Our small team focuses on creating in-depth product and service review content. To date, we’ve published countless reviews of garden, lawn, and outdoor products—from fertilizer and garden hoses to patio furniture and snow blowers.

Once we conclude our research, we craft a comprehensive, user-friendly article of recommended products and additional information to help our readers make the best purchase.

To share feedback or ask a question about this article, send a note to our team at reviews@thisoldhousereviews.com.